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This enzymatic degradation is entirely dependent on the methylation cycle, which relies on methylcobalamin to produce the universal methyl donor, SAMe

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The liver is accountable for producing triacylglycerides (TG) and transforming TG into very-low-density lipoprotein (VLDL) cholesterol, which is then carried to peripheral tissues

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Age : As we age, our bodies naturally absorb B12 less efficiently