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The success of semaglutide opened doors for an entirely new category of obesity treatment

In the intention-to-treat biopsy population, approximately two-thirds of the patients in the semaglutide arm achieved resolution of steatohepatitis without worsening of fibrosis compared with about one-third in the placebo arm

Because induction to buprenorphine in the age of fentanyl is uncomfortable and can take several days to stabilize a patient on a therapeutic dose, the use of naloxone prior to buprenorphine can aid in a safe and rapid transition to buprenorphine treatment, without the effect of unintended prolonged precipitated withdrawal which can occur following the displacement of fentanyl by buprenorphine on the mu-opioid receptor

Dosage and Administration: Semaglutide is available as a self-administered injection typically administered once weekly

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