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Clinical relevance of the ACTL6A-GCLC-GSH metabolism axis in ferroptosis of GC cells Next, we sought to determine the clinical relevance of ACTL6A in regulating GCLC and inhibiting ferroptosis in a patient-derived xenograft (PDX) model
To this end, several flavonoids have shown the capacity to inhibit signal transduction mediated by Cyclooxygenase-2(COX-2), including 10 M of luteolin, apigenin, and quercetin
Unless stated otherwise, data represent the mean of at least two independent experiments with duplicate or triplicate samples in each experiment, and error bars show the standard deviation (SD)
This trend is also seen in Figure 2G , which presents a scatter plot of the study group subtraction from control group
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