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Even though human studies have not shown the same effect, these drugs should not be used by people with a personal or family history of multiple endocrine neoplasia syndrome type 2 (MEN 2), a rare cancer that increases the risk for thyroid tumors

Deficiency rates in GLP-1 users, per Butsch et al., 2025: vitamin D 7.5% at 6 months rising to 13.6% at 12 months

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Future studies should include newer GLP-1 receptor agonists and combinations, Orandi said

Glucose tolerance test in model mice Male KM mice age 6-8 weeks with a weight of 18-25 g were selected and injected with STZ at a dose of 40 mg/kg per mouse to establish a mouse model of IGT

And they exist because GLP-1 medications work in part by slowing gastric emptying, which is the rate at which food moves through your stomach