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Furthermore, SFN orchestrates a multi-pronged assault on cancer cells by promoting the acetylation of non-histone proteins such as p53, and synergistically activating critical pathways including cell cycle arrest, apoptosis, and sensitization to other therapeutic agents like TRAIL, which is particularly promising for targeting therapy-resistant cases (66)

Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center

Certain medications can also stimulate melanin production, leading to hyperpigmentation as a side effect

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However, they will only address the symptoms and not the root causes of the autoimmune disorder

Effect of mancozeb on hepatic glutathione S-transferase in rat