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GLP-1 receptor agonists and dual GLP-1/GIP receptor agonists: strengthened warnings on acute pancreatitis including necrotising and fatal cases
Yaksh et al
GABAergic System Interaction BPC-157 demonstrates significant interactions with the GABAergic neurotransmitter system, which has implications for both its neurological effects and its gut-healing properties (given the gut-brain axis connection)
PMID 35337622
Rather than acting within a single pathway, these compounds are studied for their roles across interconnected systems, where inflammatory signaling, tissue adaptation, and immune modulation form a continuous network
No human RCT in IBD or leaky gut has been completed
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