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The exclusion follows CMS guidance issued January 2024 clarifying that anti-obesity medications are not Essential Health Benefits under the Affordable Care Act, even when the same molecule (semaglutide) is FDA-approved for both diabetes and obesity under different brand names

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Semaglutide, a GLP-1 receptor agonist used for type 2 diabetes and weight management, requires careful temperature control to maintain its effectiveness

The REDEFINE 2 trial examined the combination in adults with type 2 diabetes, where weight loss is typically harder to achieve due to insulin resistance and medication effects

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Men dealing with stress-related or psychological sexual dysfunction may also find PT-141 worth considering, since its mechanism works through the brain, not the vascular system