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GLP-1 medications can deliver significant weight loss results, but high price tags can make them difficult for many to access or stay on often because of inconsistent or nonexistent insurance coverage

Among patients with preexisting CVD, GLP-1 receptor agonists with a proven cardiovascular benefit are indicated as add-on to metformin therapy

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Rat studies have noted embryofetal mortality, structural abnormalities, and alterations to growth at maternal exposures below the maximum recommended human dose (MRHD) based on exposure AUC

While injectable medications such as Ozempic, Wegovy, Mounjaro, and Zepbound remain widely used, several oral GLP-1 medications are now available

Safety and Tolerance Current research suggests that Allulose is generally recognized as safe (GRAS), with no major safety concerns identified across studies ranging from single doses to about 12 weeks of use