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Comprehensive Assessment: Undergo a thorough evaluation, including body composition analysis, metabolic testing, and assessments for underlying conditions

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Conclusion The current evidence suggests a possible association between use of GLP-1RA and an increased risk of depression, but overall risk seems to be dominated by population characteristics, drug class, and how mood outcomes are assessed

Conklin DJ, Haberzettl P, Prough RA, Bhatnagar A: Glutathione-S-transferase P protects against endothelial dysfunction induced by exposure to tobacco smoke

Bannerjee for statistical support