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Polygonum Multiflorum Root Extract (He Shou Wu): Highly regarded in traditional medicine for its ability to stimulate the hair follicle's transition into the anagen (growth) phase and potentially reduce premature graying by supporting melanin production

Sitagliptin and metformin immediate-release coadministration provided significant improvements in A1C, FPG, and 2-hour PPG compared to placebo, to metformin immediate-release alone, and to sitagliptin alone (Table 9, Figure 1)

Berberine is another supplement some users combine with semaglutide for additional metabolic support, though it should be introduced carefully due to its own effects on the gut microbiome

2014 Oct;84(4):821-5

Metformin is the first-line medication for diabetes care, which is given as a long-term treatment

The Benefits of GLP-1 Agonists Help your body work with you, not against you