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Participants lost weight steadily for 16 months before plateauing

Although the degradation of glutathione contributes to the cysteine pool, the resulting levels are not sufficient for normal metabolism upon cystine scarcity

Current ferroptosis research on the GCH1-BH4 axis remains confined to abundance/activity metrics (transcriptional control, protein level fluctuations, BH4 synthesis rate), leaving its post-translational landscape virtually unexplored

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Disease Susceptibility Awareness The early identification of health risks strengthens strategies to prevent chronic diseases