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Additional risk factors commonly present in patients prescribed GLP-1 receptor agonists include: Reduced physical activity and prolonged immobility Hypertension and other cardiovascular comorbidities Dyslipidaemia contributing to atherosclerosis Advanced age , as thrombotic risk increases with ageing Other important VTE risk factors include: Previous VTE or family history of clotting disorders Thrombophilia (inherited or acquired clotting disorders) Active cancer or cancer treatment Oestrogen-containing medications (HRT, combined oral contraceptives) Pregnancy and postpartum period Recent surgery, trauma or hospitalisation Long-haul travel with prolonged immobility Smoking When patients taking GLP-1 receptor agonists experience thrombotic events, it is important to consider these pre-existing risk factors as they often contribute significantly to clotting risk in this population

This peptide has been studied for its potential role in cellular migration, tissue repair, and angiogenesis (formation of new blood vessels)

In Huntingtons disease, caused by polyglutamine expansions in the Huntingtin protein, curcumin reduced photoreceptor degradation and motor impairment in Drosophila models (413)

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We also showed that GSH/GSSG and NADP + /NADPH ratios were reduced in ACTL6A-KD cells (Fig