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Tumor cells acquire Cys indirectly via peripheral glutamine using System X c as a carrier, SLC7A11 is upregulated in one-third of TNBC cells in vivo , and limiting glutamine uptake or inhibiting System X c activity increases intracellular ROS levels and slows TNBC metabolism (Timmerman et al., 2013)

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Triple therapy utilizing vitamin E, milk thistle, and carnitine improves ALT and the metabolic abnormalities associated with NAFLD

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