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Vitamin B 12 deficiency, like folate deficiency, may lead to decreased synthesis of methionine and S-adenosylmethionine (SAM), thereby adversely affecting methylation reactions

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Can vitamin B12 injections help with fatigue and low energy levels

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It is common for those who follow vegetarian or vegan diets to be vitamin B12 deficient the majority of the population relies on the consumption of meat in order to maintain a healthy level of vitamin B12

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Conservative approaches such as meditation and mindfulness may be suggested along with medications such as low dose antidepressants (which are used off label for these conditions)

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