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doi: 10.1016/j.rec.2025.02.006 76 RangaswamiJBhallaVde BoerIHStaruschenkoASharpJASinghRRet al

Earlier concerns regarding acute pancreatitis and pancreatic cancer have largely been alleviated by long-term randomized trials that have not confirmed a causal association, although reporting biases and diagnostic complexity remain considerations, and continued pharmacovigilance is recommended

Over the last several years, medications that act on natural gut hormones, such as GLP-1 (glucagon-like peptide 1) and GIP (glucose-dependent insulinotropic polypeptide) receptor agonists, have revolutionized the treatment of type 2 diabetes mellitus and obesity

Plenty of natural supplements can do it as well (albeit not to the same degree as a GLP-1 agonist medication)

Heres what usually happens in those early weeks: Reduced appetite Mild weight drop Better control of cravings Over time, a lot more change can be seen

Your Weight-Loss Drugs Are Next on the Corporate Chopping Block wsj.com A standard 12 month PA doesn't cut it for GLP-1s