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Similarly, the STEP 5 trial demonstrated even greater results, with participants achieving a mean weight loss of -15.2% after two years (104 weeks)
Kafeel, M
The gradual titration schedule is evidence-based and designed to optimize both efficacy and tolerability over the full treatment course
The Role of Leptin-Melanocortin System and Human Weight Regulation: Lessons from Experiments of Nature
Kroetz et al., 2019)
Sarma GN, Savvides SN, Becker K, Schirmer M, Schirmer RH, Karplus PA (May 2003)
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