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N Engl J Med 2016;375:183444

It plays a crucial role in overall health and well-being

[PubMed | ClinicalTrials.gov | DOI] Rubino D, Abrahamsson N, Davies M, et al

When lean mass decreases significantly during weight loss, performance can change even if total body weight improves

However, it quickly began apparent that one notable effect was the ability of semaglutide to also cause decreases in weight

As senescent cells rely on glutaminolysis to neutralize their acidic intracellular pH by providing ammonium ions 90 , reduced signature of glutamate-related pathways support the anti-senescent properties of MOTS-c in -cells