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Gradual dose escalation is used to minimise gastrointestinal side effects such as nausea, vomiting, and diarrhoea, which are most common at higher doses

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This includes checking for problems like obstructive sleep apnea or gallbladder disease

Many patients using these medications have reported positive experiences, particularly regarding weight management

The most common side effects at higher doses (8 mg and 12 mg weekly) are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation

doi: 10.1186/1471-2202-13-33 145 GaberySSalinasCGPaulsenSJAhnfelt-RnneJAlanentaloTBaqueroAFet al