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PMID 23479637

In the M-ARCOL model (Mucosal Artificial Colon, an advanced in vitro system using microbiota from healthy donors), daily exposure to PEMPs for 14 days increased pathobiont Desulfovibrionaceae (Fournier et al., 2023)

For example, polylactic acid (PLA), polyethylene terephthalate (PET) and polyethylene (PE) are found in bottles, polyhydroxyalkanoates (PHA) are used in disposable items, polycaprolactone (PCL) is common in medical devices and food packaging, polypropylene in clothing, polystyrene in food containers, and polyurethane is found in tires, furniture, and insulation (Iwata, 2015

The "rapid reversal" group (approximately 10-15% of users) experiences concerning quick benefit loss within weeks of discontinuation, typically involving users who applied very high concentrations creating dependency-like patterns, possessed severe underlying skin conditions requiring ongoing treatment, experienced significant lifestyle or environmental stressors overwhelming skin resilience, discontinued abruptly without tapering from high-dose protocols, or had unrealistic perception inflation during treatment leading to exaggerated reversal perception

It violates the spirit of sport (this definition is outlined in the Code)

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