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MOTS-c is a mitochondrial peptide being investigated for metabolism, insulin sensitivity, energy balance, and mitochondrial function
They are generally recommended for overweight individuals or those with obesity who also have related health conditions such as diabetes, prediabetes, or hypertension
For comparison, phentermine alone typically produces 5 to 7% weight loss over similar periods, and orlistat (Xenical) produces 3 to 5%
The semaglutide energy guide addresses this question with nuance
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