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Por ello, la Sociedad Alemana de Nutricin no ha indicado unas dosis diarias necesarias

Because NHIS does not include information on all weight-related conditionssuch as obstructive sleep apnea, peripheral arterial disease, and aortic atherosclerosisthe number and share of the private and ESI markets indicated for GLP-1 drugs are potentially underestimated among those who are overweight

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5,10 Moreover, the multifaceted functions of GLP-1 RAs extend into the realm of brain activity, particularly exhibiting neuroprotective effects

While it could be argued that these findings may be different if all GLP-1RAs were dose optimized in the same way, this seems unlikely given that semaglutide-induced weight loss is about two-fold greater than liraglutide (177) and three-fold greater than exenatide (143)

The standard protocol starts with 0.25mg weekly for 4 weeks, increasing to 0.5mg, then 1.0mg, 1.7mg, and finally 2.4mg weekly if tolerated