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No one warned them, Hey, youre going to have all this loose, hanging skin afterwards. In extreme cases, she adds, they almost feel a little bit deformed because of the skin. With next-generation GLP-1s, like an oral version of Wegovy and injectable retatrutide, poised to launch as early as 2026, body-contouring procedures will continue to skyrocket, says Darren Smith, MD, a board-certified plastic surgeon in New York City

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This is why progestin therapy, while helpful for some, fails completely for others

Xu Y, Van Hul M, Suriano F, Preat V, Cani PD, Beloqui A

Is it reversible

Unlike other weight-loss medications, GLP-1s mimic a gut-based, appetite-modulating hormone that decreases blood sugar levels and sends signals of fullness to the brain