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The xc- cystine/glutamate antiporter: a mediator of pancreatic cancer growth with a role in drug resistance

Wait 12 minutes to allow full absorption

In summary, arginine depletion may be a feasible approach for cancer treatment because of the anti-cancer effects reported in pre-clinical studies, the low adverse reactions and the treatment-achieved stable disease in clinical trials of advanced stage cancers

4), consistent with reduced activities of key phase I enzymes, including CYP1A2, 2C8, 2C9, 2C19, and 3A4, in patient organoids (Fig