C.YanA.ElhadadS.AvrahamT.WeitmanE.MehraraB
29,30 Genetic testing for mutations in SCN9A and SCN10 (which code for the Nav1.7 and Nav1.8 sodium channels, respectively) is commercially available and may be considered for those with a family history of neuropathic pain in the feet or for young, otherwise healthy patients
Made by cells lining the small intestine, this hormone has a host of different roles
Oral capsules or sublingual preparations deliver the peptide to the target tissue
Another challenge, researchers say, is that symptoms of nutrient deficiency including fatigue, nausea, and irritability can overlap with the common side effects of GLP-1 medications, making problems harder to spot early
Clinically, this is where things can get complicated