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Of these 36 studies, 35 were preclinical animal experiments

Another potential therapeutic, Minocycline is a microglial inhibitor which reduces BBB dysfunction by preventing production of glutamate, matrix metalloproteinases, and the proinflammatory cytokine, IL-1, and increasing the levels of cells responsible for the remyelination of neurons which would be relevant in treating AD [138, 140,141,142]

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Even if resistance can develop to different drugs, the underlying mechanisms may be similar

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Tirzepatide has its own expected appearance