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Description

It is usually related to telogen effluvium, a temporary hair shedding condition triggered by rapid weight loss and nutritional changes rather than by the medication itself

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Patients with rapid baseline gastric emptying (a condition sometimes called gastroparesis inverse, or dumping syndrome predisposition) may not experience the same satiety signal because food clears the stomach before the GLP-1R-mediated slowdown can accumulate

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therefore if transit time is less than 14 hours the patient will have hematochezia, and if greater than 14 hours the patient will exhibit melena

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Retatrutide is an investigational pharmaceutical agent currently under clinical development and does not hold a marketing authorisation from the MHRA or the European Medicines Agency (EMA)

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PMC 2427333

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