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Re-Engaging the Bodys Own GLP-1 System Rather than artificially replacing the bodys hormonal signals, another approach is to stimulate and support them naturally through food
Exenatide, the first GLP-1RA approved in 2005, demonstrated clinical efficacy but its low homology with human GLP-1 and gastrointestinal side effects restricted widespread use (Muttenthaler et al., 2021)
Retrieved 3 January 2025
In the lung, GLP-1 binding to its receptors improves lung function and reduces mortality in patients with obstructive pulmonary disease [9]
[8] U.S
It activates three receptors at once: GLP-1, GIP, and glucagon
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