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If CagriSema truly prevents the metabolic slowdown associated with weight loss, as the preclinical data suggests, it could produce more durable outcomes with less weight regain after treatment completion

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Neuroinflammation with hypometabolic lesions cause chronic cognitive impairment in COVID patients 649

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Notably, participants receiving the highest dose (12 mg) achieved an average weight loss of approximately 24.2% (around 58 pounds) over the 48-week period