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The FDAs approval of Zepbound represents a significant milestone in weight management strategies

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Eating adequate nutrition despite minimal hunger requires intentional meal scheduling rather than relying on hunger cues

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Animal model studies have suggested that GLP-1RAs may cause pancreatitis and exocrine dysplasia, but in the large RCTs and a meta-analysis, GLP-1RAs did not increase the risk of pancreatitis or pancreatic cancer [82,83]

This would have put the drug ahead of rival Novo Nordisks semaglutide, which scored 42% pain reduction in a previous trial