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Wiffen PJ, Derry S, Bell RF, et al

10.1128/AEM.70.7.4222-4229.2004

This seems counterintuitive

Weight Regain: A Common Challenge Studies show that discontinuing GLP-1 agonists frequently leads to weight regain and a return of cardiometabolic issues that improved while on the medication.(3, 4) An analysis of 327 individuals who used GLP-1 medication for 68 weeks found that after stopping the treatment, they regained approximately two-thirds of the weight they had initially lost

Despite the lower doses, the results remain impressive

Trimi's compounded preparations are prepared per individual prescription and are not themselves FDA-approved as drugs