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High-dose magnesium citrate (typically 10 oz of liquid preparation containing 1.745 g to 1.9 g magnesium citrate, per OTC labeling) used for bowel preparation or acute constipation relief can cause significant diarrhea, cramping, and electrolyte shifts

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Uchida Y, Ohtsuki S, Katsukura Y, Ikeda C, Suzuki T, Kamiie J, Terasaki T