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The underlying mechanisms have not been fully delineated but are likely to involve modulation of the brain dopamine reward system via GLP-1 receptors, which are present both in the ventral tegmental areas (VTA), where dopamine neurons are located, and in the nucleus accumbens (NAc), which is the main projection of VTA dopamine neurons 14
This indicates high public interest in GLP-1 RAs and highlights priorities for clinical and policy communities, including monitoring side effects, addressing access barriers, and acknowledging both the physical and psychological benefits of these drugs
Hence, this review presents the current understanding of the role of glutathione and glutathione-associated enzymes in the susceptible and resistant responses of plants to viruses
