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When the rectum becomes distended with stool, it can press against the bladder, reducing its capacity and preventing complete emptying

PMCID: PMC9542252.

The drugs mimic a naturally occurring hormone in the body that helps regulate blood sugar and promotes a feeling of fullness

When viral infections or chronic inflammation overwhelm the body, glutathione stores can become severely depleted or functionally impaired, leading to a cascade of cellular damage

Starting at 2 mg and escalating slowly is KEY, as the Phase 2 data showed a lower starting dose of 2 mg produced meaningfully fewer GI side effects than jumping in at 4 mg

The program also reflects a broader policy priority of increasing access to high-value treatments while controlling healthcare costs