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Nat Med (2021) 27(4):60115
The funnel plot showed a symmetrical distribution, indicating no publication bias, supported by Eggers test (p = 0.16) and Beggs test (p = 0.73), with no imputed studies found using the trim and fill model
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Indeed, patients with CD show high cardiovascular risk due to the presence of many cardiovascular risk factors such as hyperglycaemia and dyslipidaemia, but also endothelial dysfunction and chronic inflammation and for this reason cardio-protection is strongly required (117)
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