Nauck MA, Frossard JL, Barkin JS, Anglin G, Hensley IE, Harper KD, et al
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Within days to weeks, patients typically experience return of appetite, faster stomach emptying, and gradual weight regain as the medication's effects diminish
Arterioscler Thromb Vasc Biol 37(12):22522259 Kitabchi AE, Wall BM (1995) Diabetic ketoacidosis
By the time Knudsen returned from maternity leave in 1994, all of her former colleagues had left and the future of the GLP-1 project looked bleak
With so many steps the process has a failure rate of about 20% for peptides above 30 amino acids, leaving a lot of impurities to remove