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Retatrutide hits 28% weight loss in Phase 3 A summary of the interesting content that I consumed this past week What I Read This Week: a summary of the content that I consumed this past week Caught My Eye 1) Retatrutide hits 28% weight loss in Phase 3 On May 21, Eli Lilly released Phase 3 results for retatrutide from the 2,339-patient TRIUMPH-1 obesity trial
All viral glycoproteins share the characteristic of their assembly into oligomers that necessitates the formation of a disulfide bond and this is inhibited by the reducing action of GSH
Patients on Multiple Hepatically Cleared Medications A patient already taking minoxidil, finasteride (CYP3A4 substrate), and a statin (CYP3A4/CYP2C9) has a more crowded hepatic field than someone on minoxidil alone
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Interestingly, the superiority analyses showed heterogeneous results among these trials
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