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The drugs work by mimicking a hormone called glucagon-like peptide-1 (GLP-1) that is released in the gut in response to eating
Some people notice appetite changes early with certain medications
The knee-pain and sleep-apnea benefits are the downstream payoff of that weight reduction plus retatrutide's anti-inflammatory and metabolic effects
Combining a GLP-1 with sertraline does not replace mental-health care
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How does tirzepatide differ from GLP-1 agonists
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