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Under basal conditions, KEAP1 sequesters NRF2 within a complex with Cullin 3 (CUL3), which is an ubiquitin ligase E3 that targets NRF2 for proteosomal degradation (Kobayashi et al., 2004)
Li Y, Huang T, Zheng Y, Muka T, Troup J, Hu FB
Beyond this threshold, biological activity becomes inconsistent and unpredictable research results lose reproducibility
Immunohistochemical localization of modified C-reactive protein antigen in normal vascular tissue
Although a minor inhibition of the ER stress response by GSTP1 was observed (comparing corresponding curves in Figures 7AD ), no statistical difference was found between mock- and GSTP1 -transfected cells
