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Causes of insomnia may include: stress disruptions to the internal body clock, due to travel or work commitments poor sleep habits, such as an irregular bedtime schedule eating late in the evening mental health conditions, such as anxiety and depression neurodegenerative conditions, such as Alzheimers disease neurodevelopmental conditions, such as attention deficit hyperactivity disorder (ADHD) certain medications, such as those for depression, asthma, and high blood pressure sleep-related disorders, such as sleep apnea and restless legs syndrome consuming alcohol, nicotine, and caffeine Deficiencies or higher levels of the following vitamins may impact sleep: Vitamin D Studies indicate vitamin D levels also support pathways that regulate melatonin

pylori infection raises the vulnerability of cells to ferroptosis, and PHKG2 boosts RSL3-triggered ferroptosis in H

It could be contaminated with other banned substances, heavy metals, or bacteria

IGF-1 plays a major role in muscle growth, cellular repair, and tissue regeneration by stimulating protein synthesis and cellular proliferation

Human trial data is limited to a handful of small pilot studies, and a 2025 University of Utah review concludes BPC-157 should be considered investigational