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This paper presents a study carried out by the DiARC-UNINA group, developed within the WP4 - Spoke 1 of the PE5 CHANGES research project "Cultural Heritage Active Innovation for Next-Gen Sustainable Society", entitled "Strategies4Changes"

Retatrutide's Phase 2 trial data (Jastreboff et al., NEJM 2023) identified a side-effect profile broadly consistent with other incretin-based therapies: Gastrointestinal : Nausea, vomiting, diarrhoea, and constipation were the most commonly reported adverse effects, particularly during dose escalation

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Subsequently, supraphysiological doses of Fe can catalyze lipid peroxidation by promoting Fenton reactions or activating iron-dependent enzymes, thereby facilitating ferroptosis [54]