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Surgical interventions impose unique metabolic and inflammatory stressessuch as ischemiareperfusion injury, anesthetic exposure, and systemic inflammatory responsesthat impair immune cell bioenergetics and redox balance

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8,39 In practice, however, basal insulin is usually considered as a later therapy option for patients with T2D inadequately controlled on other therapies (Figure 1)

[4] And if you want to avoid pregnancy, its vital to understand how the treatment interacts with oral contraceptives and birth control to stay protected

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