20 Although the disabilities of PD may provoke depression in some instances, the underlying biochemical changes in the brain associated with PD pathophysiology also predisposes for endogenous depression
The influence on the BPC-157 dopamine system, in particular, may explain some of the behavioral effects observed in animal studies, including antidepressant-like and anxiolytic-like activities
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FIGURE 2 Lut ameliorates the deposition of ECM proteins in the kidneys of IgAN mice Prolonged inflammation and oxidative stress led to the expansion of the mesangial matrix, resulting in the progression of renal fibrosis in IgAN mice, as indicated by a significant increase in the area of fibrosis in their kidneys compared with that in control mice
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Biochem Biophys Acta 1822:625630 Schachter AS, Davis KL (2000) Alzheimer's disease
