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Compounded GLP-1 medications contain compounded formulations of the active ingredient as brand-name products but aren't the same product, aren't FDA-approved, and should never be represented as equivalent to or interchangeable with FDA-approved medications

Stopping tirzepatide will lead to weight regain, which will worsen the metabolic conditions that drive ED

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Initial Management and Education Starting Dose: Semaglutide 0.25 mg once weekly (to minimize gastrointestinal side effects), with a plan to titrate to 1.0 mg weekly over several weeks

In addition,meta-analysessuggest that GLP-1 RAs may actually improve bone density in the lumbar spine and hip compared with controls. Any rapid weight loss, including from calorie restriction or bariatric surgery, is likely to be associated with some bone loss, so I do not think blaming GLP-1s is the answer, she added