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The nausea is both dose-dependent and time-dependent, meaning higher doses produce more nausea, and symptoms are most prominent during treatment initiation before the body adapts to the medications effects
Longer studies show 3 to 8 percent weight loss over 6 to 12 months
Not catastrophically wrong, but wrong enough to leave results on the table
2022;377:eabq1841
It is a real drug with real constraints, not a stick-on sticker
They have shown a further reduction of HbA1c percentage between 0.5 and 0.7 in this combination and in some studies a lower rate of hypoglycaemic events was observed (12, 18, 21, 31)
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