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doi: 10.3389/fvets.2021.769837 26 GalvisRDMadridLVRamrez-VsquezN

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The high variability (CV 50%80%) was accepted because: (1) the patient population was already dose-optimized, (2) growth hormone suppression integrates over time (AUC-driven), and (3) the indication did not require treatment-nave dose finding

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