The positively charged ammonium group of carnitine is coordinated by conserved hydrophobic residues that form an aromatic cage around carnitine (Fig
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In addition, its multi-target mechanisms such as anti-inflammatory, promoting synaptic plasticity and antioxidant make it unique in improving diseases such as neurodevelopmental disorders and epilepsy, reducing inflammatory responses, enhancing neuronal connections, and scavenging free radicals, thereby improving patients' cognitive function and neurodevelopment in an all-round way
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