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doi: 10.1016/j.carres.2012.05.007 46 LiZ.HeB.GaoY.CaiL
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Nofreezing denatures the peptide structure and renders tirzepatide ineffective
These advancements are particularly relevant given that resveratrols systemic bioavailability remains below 5% in humans due to extensive first-pass metabolism, as shown in pharmacokinetic studies using 14C-labeled resveratrol [148]
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