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Over a 20-year period, Simeons placed 500 patients on a strict weight loss regimen for 40 days: two daily meals consisting of lean meat, leafy vegetables, and fruit for a total of 500 calories a day, along with a daily shot of HCG

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After figuring out how to increase the amount of time exendin was active in the body, Eng, who worked at the Bronx Veterans Affairs Medical Center, created the first GLP-1: Exenatide