In the Phase IV study, semaglutide will be evaluated for its effects on improving depressive symptoms over 26 weeks in patients with major depressive disorder who also have overweight or obesity ( ID NCT07136714)
Diane Schram, 64, lost 25 pounds with Ozempic and tirzepatide, a similar medication
Recovery takes longer
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In the pivotal SURPASS trials evaluating tirzepatide for type 2 diabetes, nausea occurred in 1222% of patients depending on the dose (5 mg, 10 mg, or 15 mg weekly), compared to approximately 58% with placebo
Sabbour H, Almahmeed W, Alawadi F, Shehab A, Al Zubaidi A, Bashier A, et al