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A hallmark of P.g s systemic effect is the disruption of immune homeostasis, notably a skewing towards a pro-inflammatory state characterized by an imbalance between Th17 cells and Treg cells in the gut, mesenteric lymph nodes, and spleen (Jia et al., 2024

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This mechanical effect contributes to prolonged satiety and can make large meals or rich, sweet foods feel less appealing or even uncomfortable

received funding from the National Institutes of Health National Center for Advancing Translational Sciences (grant #UL1TR003163)

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